Progesterone softgel capsule is indicated in-
Maintenance of Pregnancy in cases of Threatened / Recurrent abortion.
Luteal support during IUI and ART procedures IVF-ET.
Luteal support in cases of proven luteal phase insufficiency.
Along with estrogen in post-menopausal hormone replacement therapy (HRT) either in sequential or in continuous regimen.
To prevent endometrial hyperplasia where endogenous estrogen is present.
As progesterone challenge test in secondary amenorrhoea.
For cycle control along with estrogen therapy.
Dysfunctional uterine bleeding (DUB)
Premenstrual tension.
Endometriosis.
Oocyte donation programme.
Benign mastopathy.
Ketoconazole inhibits the metabolism of progesterone.
Progesterone is devoid of estrogenic, androgenic and mineralocorticoid effects. Mild somnolence and other CNS side effects like depression, breast tenderness and bloating are reported. Side effects are less when vaginal route is used.
