In vitro studies showed that a pH lowering effect and sperm motility reduction contribute to the activity of this gel in the vagina. Systemic exposures of Lactic Acid, Citric Acid and Potassium Bitartrate following vaginal administration of this gel are not expected to lead to safety concerns. In vitro studies with commonly used vaginal preparations (Miconazole, Metronidazole, Tioconazole, and a product for maintaining normal vaginal pH) showed no significant effect on the pH or buffering capacity of this gel.
This gel may be used concomitantly with other products for vaginal infections including Miconazole, Metronidazole and Tioconazole.
Avoid the use of this gel with vaginal rings.
Most common side effects are vulvovaginal burning sensation, vulvovaginal pruritus, vulvovaginal mycotic infection, urinary tract infection, vulvovaginal discomfort, bacterial vaginosis, vaginal discharge, genital discomfort, dysuria and vulvovaginal pain.
There is no use for this gel in pregnancy.
Cystitis and Pyelonephritis: Avoid use in women with a history of recurrent UTI or urinary tract abnormalities.
In case of overdose, seek emergency medical attention.