Description

Succinylcholin, MAOIs (monoamine oxidase inhibitors), β2-blockers, corticosteroids, diuretics, muscle relaxants, sympathomimetic xanthine derivatives. Bambuterol may partly or totally inhibit the effect of β-blockers.

Common side effects are fatigue, nausea, palpitation, headache, dizziness & tremor.

Pregnant women: There is no definite evidence of ill consequence during pregnancy. Nevertheless, the drug should not be used during the first trimester of pregnancy, unless the expected benefit is thought to outweigh any possible risk to the fetus. Lactating mother: It is excreted in breast milk. So, patients taking this drug should not breast-feed.

Reduce the dose in renal impairment, avoid in cirrhosis and severe hepatic impairment. Caution should be observed in patients with severe cardiovascular disorder, such as ischaemic heart disease, tachyarrhythmias or severe heart failure.

Impaired renal function (GFR 50 ml/min): The recommended starting dose is 5 mg, which may be increased to 10 mg after one to two weeks, depending on the clinical effect. Impaired hepatic function: Not recommended because of unpredictable conversion to terbutaline.

Short-acting selective & β2-adrenoceptor stimulants

Keep away from light, store in a cool and dry place. Keep out of reach of children.