Each vaginal suppository contains-
Metronidazole BP 200 mg
Neomycin Sulphate BP 35000 IU
Polymyxin B Sulphate BP 35000 IU
Nystatin BP 100000 IU.
Metronidazole, a nitroimidazole, is active against various anerobic bacteria and protozoa. Nystatin is a polyene antibiotic with antifungal activity. Neomycin is an aminoglycoside. It is bactericidal and active against some gram-positive and gram-negative organisms. Polymyxin is active against gram-negative organisms including Pseudomonas aeruginosa.
One suppository in the vagina at bedtime for 12 days or as directed by the physician.
Contraindicated to the patients who are hypersensitive to Metronidazole, Neomycin Sulphate, Polymyxin B Sulphate and Nystatin.
Skin rash, urticaria may occur rarely.
Caution should be practiced in pregnancy and lactation.
Caution should be taken in case of renal impairment.
Drugs used in Vaginal and Vulval condition
Store in a cool and dry place, away from light & children.