Drugs that may interact with Zuclopenthixol include:
tricyclic antidepressant medicines
guanethidine and similar medicines (used to lower the blood pressure)
barbiturates and similar medicines
levodopa and similar medicines (used to treat Parkinson’s disease)
metoclopramide (used in the treatment of gastro-intestinal disorders)
other antipsychotic medicines (e.g. thioridazine)
medicines that change the heartbeat (e.g. quinidine, amiodarone, sotalol, erythromycine, moxifloxacin, lithium)
Common side effects are Racing heart (tachycardia), a sensation of a rapid, forceful, or irregular beating of the heart (palpitations) Tremor, twisting or repetitive movements or abnormal postures due to sustained muscle contractions (dystonia), increased muscle stiffness (hypertonia).
The safe use of zuclopenthixol during pregnancy has not been established. Zuclopenthixol is excreted in human milk. The safe use of zuclopenthixol during lactation has not been established.
Caution should be taken if-
you have used zuclopenthixol or any other treatment for schizophrenia before and if you had any problems
you are taking any other prescription or non-prescription medicines
you are pregnant or thinking of becoming pregnant, or if you are breast-feeding
you regularly drink a lot of alcohol
you have any liver problems, Parkinson’s disease or have ever had seizures
you have dementia
you have glaucoma
you have any kidney problems
you have risk factors for stroke (e.g. smoking, high blood pressure).
you have hypokalemia or hypomagnesia (too little potassium or magnesium in your blood)
you have a history of cardiovascular disorders
you or someone in your family has a history of blood clots
you are being treated for cancer (applies to zuclopenthixol Depot only)
you use any other antipsychotic medicine
The safety and efficacy of zuclopenthixol in children under the age of 18 years have not been established, therefore its use is not recommended.
Symptoms of overdose may include: somnolence, coma, unusual movements, convulsions, shock, high or low body temperature
Phenothiazine related drugs
Should be stored between 15°C and 25°C. Protect from light.