Description

Nebivolol: Class I & III Antiarrhythmics, Calcium channel blocker (Verapamil/Diltiazem) Centrally-acting antihypertensives, Anaesthetics Antipsychotics, Antidepressants, NSAIDs Hydrochlorothiazide: Drugs affecting Potassium & Calcium level Non-steroidal anti-inflammatory drugs (NSAIDs) Concomitant administration of this combination with Antipsychotics, Tricyclic Antidepressants & Barbiturates may enhance the hypotensive effect and lead to postural hypotension.

Nebivolol: Headache, Dizziness, Tiredness, Diarrhoea, Constipation, Nausea etc. Hydrochlorothiazide: Vertigo, Itchiness, Rash, Increased sensitivity of skin to sunlight etc.

This combination is not recommended during pregnancy. It is also not recommended for mothers who are breast-feeding

Nebivolol: Beta-blockers should not be used in patients with untreated Congestive Heart Failure (CHF) & bradycardia. In patients with Chronic Obstructive Pulmonary Diseases (COPD), beta-blockers should be used with caution as airway constriction may be aggravated. Hydrochlorothiazide: In patients with renal disease, thiazides may increase azotaemia. If progressive renal impairment becomes evident, careful reappraisal of therapy is necessary. Thiazides can cause fluid or electrolyte imbalance. Thiazides may decrease urinary calcium excretion and may cause slight elevation of serum calcium in the absence of known disorders of calcium metabolism

Use in children is not recommended.

No data are available on Overdosage. Overdosage with Hydrochlorothiazide is associated with electrolyte depletion and dehydration resulting from excessive diuresis.

Combined antihypertensive preparations