{"indications":"\"\"","description":"\"\"","pharmacology":"\"\"","dosage":"\"No dosage adjustment is recommended when valacyclovir is coadministered with digoxin, antacids, thiazide diuretics, cimetidine or probenecid in subjects with normal renal function.\"","interaction":"\"The most frequently reported adverse reactions were nausea (15%), headache (14%), vomiting (6%), dizziness (3%) and abdominal pain (3%).\"","contradiction":"\"Pregnancy category B. Valacyclovir was not teratogenic in rats or rabbits at 10 and 7 times human plasma levels, respectively, during the period of major organogenesis. There is no adequate and well-controlled studies of valacyclovir in pregnant women. \\n\\nNursing Mothers: Unchanged valacyclovir was not detected in maternal serum, breast milk, or infant urine. Valacyclovir should be administered to a nursing mother with caution and only when indicated.\"","side_effects":"\"Dosage reduction is recommended when administering valacyclovir to patients with renal impairment. Similar caution should be exercised when administering valacyclovir to geriatric patients and patients receiving potentially nephrotoxic agents. The safety and efficacy of valacyclovir have not been established in immuno compromised patients other than for the suppression of genital herpes in HIVinfected patients\"","pregnancy":"\"Pediatric Use: Safety and effectiveness of valacyclovir in pre-pubertal pediatric patients have not been established. \\n\\nElderly Use (Over 65 yr.): Elderly patients may require a dose reduction of valacyclovir due to a low body weight or disorders (renal, CNS etc.) associated with aging.\"","precautions":"\"Herpes simplex & Varicella-zoster virus infections\"","therapeutic":"\"Store in cool & dry place, away from children.\"","storage":"\"\""}